How Semaglutide Supports Weight Loss

How Semaglutide Supports Weight Loss

Introduction

Losing weight can be challenging, especially when lifestyle changes alone aren't enough. For many people, diet and exercise do not lead to long-term results. That’s where medical weight loss options like Semaglutide come in. Originally developed to treat type 2 diabetes, this medication is now gaining attention for its impact on weight management. With proper use and guidance, it can support lasting lifestyle change.

What Is Semaglutide and How Does It Work?

Semaglutide is a type of GLP-1 receptor agonist. This means it mimics the hormone glucagon-like peptide-1. In the body, GLP-1 helps regulate insulin, control blood sugar, and manage hunger signals.

When taken regularly, Semaglutide slows down digestion and helps you feel full longer. It reduces the urge to overeat, which leads to a natural calorie deficit. Consequently, patients taking the medication often notice a reduced appetite and fewer cravings.

Unlike stimulant-based medications, Semaglutide works with your body’s natural systems. Making it a gentler and more targeted option.

Approved Uses and Forms of Semaglutide

Semaglutide was first approved to treat type 2 diabetes under the brand name Ozempic. Later, a higher-dose version called Wegovy was approved specifically for chronic weight management.

The drug is typically administered as a once-weekly injection. However, oral versions are also available for diabetes care, although not usually for weight loss.

Importantly, this treatment is meant for people with a body mass index (BMI) over 30. Or over 27 with weight-related conditions such as hypertension or sleep apnoea.

How Semaglutide Helps with Weight Loss

The success of Semaglutide in weight loss comes down to four key mechanisms:

• Reduces appetite: Patients feel full faster and stay satisfied longer after eating.
• Slows stomach emptying: Digestion takes longer, which extends feelings of satiety.
• Improves insulin response: Helps manage blood sugar, preventing energy crashes and cravings.
• Targets fat stores: By supporting calorie deficits, fat loss occurs more consistently over time.

Because of these effects, clinical trials have shown that patients can lose up to 15% of their body weight. 

What to Expect During Treatment

If your clinician recommends Semaglutide, your treatment journey begins with a thorough assessment. This includes checking your medical history, current weight, and blood pressure. If suitable, you’ll be prescribed a starter dose that increases gradually over weeks.

This step-by-step dosing helps your body adjust and reduces discomfort. Common experiences during treatment include:

• A noticeable drop in hunger levels
• Slower meal consumption
• Fewer cravings between meals
• Gradual, steady weight loss

You’ll also receive support from a dietitian or medical team to maximise success. This might involve food journaling, weekly weigh-ins, and personalised coaching.

Semaglutide vs Other Weight Loss Medications

Unlike older weight loss drugs, Semaglutide does not rely on appetite suppression through stimulants. This results in fewer side effects related to heart rate or nervous system activity.

Here’s how it compares to other treatments:

• Orlistat: Blocks fat absorption but can cause digestive upset.
• Phentermine: A stimulant that reduces appetite but may raise blood pressure.
• GLP-1 analogues: Work through gut hormones for safer, sustained results.

Because Semaglutide works holistically and fits well it’s quickly becoming a preferred choice for doctors and patients.

Conclusion

Semaglutide has changed the landscape of medical weight loss. It offers people struggling with obesity a chance to lose weight and keep it off. By targeting appetite, digestion, and hormonal balance, it works with your body—not against it. When paired with lifestyle changes and professional support, it can make a lasting impact on your health and confidence.

For more information and to book a consultation visit the ACIBADEM Beauty Center Weight Loss page.